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Pharmacological and antioxidant actions of garlic and.or onion in non-alcoholic fatty liver disease (NAFLD) in rats

Abstract Non-alcoholic fatty liver disease (NAFLD) includes a broad spectrum of fat-induced liver injury, ranging from mild steatosis to cirrhosis and liver failure. This study investigates the hepatoprotective properties of garlic and onion in NAFLD rat model. Ninety male Sprague-Dawley rats were randomly divided into 9 groups; normal (I), NAFLD induced with high fat diet […]

Garlic powder intake and cardiovascular risk factors: a meta-analysis of randomized controlled clinical trials

Abstract BACKGROUND/OBJECTIVES: Although preclinical studies suggest that garlic has potential preventive effects on cardiovascular disease (CVD) risk factors, clinical trials and reports from systematic reviews or meta-analyses present inconsistent results. The contradiction might be attributed to variations in the manufacturing process that can markedly influence the composition of garlic products. To investigate this issue further, […]

Meta-Analysis: Does Garlic Intake Reduce Risk of Gastric Cancer?

Abstract In the past 2 decades, various epidemiological studies investigated whether garlic can positively modify the risk of gastric cancer. Garlic contains numerous sulfide compounds, including diallyl trisulfide, which have anticarcinogenic properties. We conducted a meta-analysis to determine if garlic intake reduces the risk of gastric cancer. An electronic search of MEDLINE, PubMed, and EMBASE […]

Garlic: main constituents

Garlic contains a wealth of sulfur compounds; most important for the taste is allicin (diallyl di­sulphide oxide), which is produced enzymati­cally from alliin (S-2-propenyl-L-cysteine sulfoxide) if cells are damaged; its biological function is to repel herbi­vorous animals. Allicin is deacti­vated to diallyl di­sulphide; therefore, minced garlic changes its aroma if not used imme­diately. In the […]

Garlic – part 2

Vampires have no chance in Vietnam: Freshly grated garlic is served in liberal amounts to spring rolls and soups in Northern Vietnam (see Vietnamese cinnamon for an account of the Hanoi style beef soup). The latter is an example demonstrating the subtle effect that can be achieved by adding grated or squeezed raw garlic to […]

A Systematic Review and Metaanalysis on the Effects of Garlic Preparations on Blood Pressure in Individuals With Hypertension

Abstract BACKGROUND: Many patients prefer herbal medications to conventional drugs. Limited trial evidence suggests that garlic preparations reduce high blood pressure (BP). METHODS: We searched electronic databases through March 2014 to identify all randomized controlled trials that compared a garlic preparation to placebo in hypertensive patients. Trials were required to report BP values at baseline […]

Garlic – part 1

Garlic is one of the most popular spices in the world, and wher­ever it was intro­duced to, it met enthu­siastic ap­proval. It is re­ported that in an­cient Egypt, the workers who had to build the great pyramids were fed their daily share of garlic, and the Bible mentions garlic as a food the Hebrews en­joyed during their […]

garlic -Etymology

Garlic (Old English gārlēac) is a native Germanic word being com­posed of two ele­ments: The first ele­ment gar means spear and refers to the pointed leaves. It is cognate to Gothic gaida and Old High German ger, which has survived only in a number of German first names including my own. That element ger is […]

Effects of garlic extract on spreading depression: In vitro and in vivo investigations

Abstract Objectives The potential use of garlic for prevention and treatment of different types of headaches has been suggested by several medieval literatures. Cortical spreading depression (CSD), a propagating wave of neuroglial depolarization, was established as a target for anti-migraine drugs. This study was designed to investigate the effect of garlic extract on CSD in […]

Potential protective effects of nigella sativa and allium sativum against fructose-induced metabolic syndrome in rats

Abstract Among famous medicinal plants with known antioxidant activity; black seed (Nigella sativa, NS) and garlic (Allium sativum) which have been used in traditional medicine. In recent years, rates of metabolic syndrome (MS) have been increasing globally. The present work was designed to study the potential protective effects of black seed and raw garlic homogenate […]